Gaál M, László J, Bösze P
J Clin Pathol. 1974 Dec;27(12):951-4. doi: 10.1136/jcp.27.12.951.
In 14 cases of the Turner syndrome and pure gonadal dysgenesis streak gonads were studied histologically. In cases where the 46,XX line was unimpaired the blood vessels of the gonad showed severe degeneration in at least 30 to 50%. These streak gonads usually contained some of the characteristic ovarian elements as well as the vascular lesions. In gonosomal monosomy, on the other hand, a similar intensive vascular degeneration could not be found and the gonad consisted of indeterminate connective tissue. These observations are strong indications of a close correlation between karyotype and the histology of the streak gonad, which may supply further information on the manner and timing of the development of the streak gonad.
对14例特纳综合征和单纯性腺发育不全条索状性腺进行了组织学研究。在46,XX核型未受影响的病例中,性腺血管至少有30%至50%出现严重退变。这些条索状性腺通常含有一些特征性的卵巢成分以及血管病变。另一方面,在性染色体单体型中,未发现类似的严重血管退变,性腺由不确定的结缔组织组成。这些观察结果有力地表明核型与条索状性腺组织学之间存在密切关联,这可能为条索状性腺的发育方式和时间提供进一步信息。