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1
Comparative cytogenetical and morphological studies in ovarian dysgenesis.卵巢发育不全的比较细胞遗传学和形态学研究。
J Clin Pathol. 1974 Dec;27(12):951-4. doi: 10.1136/jcp.27.12.951.
2
Laparoscopy in endocrine and genetic disorders of the gonads.腹腔镜检查在性腺内分泌和遗传性疾病中的应用。
Acta Endocrinol Suppl (Copenh). 1975;192:1-124.
3
[Morphological characteristics indicating testicular differentiation in various forms of the streak-gonad syndrome].[不同形式条索状性腺综合征中提示睾丸分化的形态学特征]
Morphol Igazsagugyi Orv Sz. 1983 Jan;23(1):41-7.
4
Gonadal dysgenesis with 45,XO/46,XX mosaicism demonstrated only in a streak gonad.性腺发育不全伴45,XO/46,XX嵌合体,仅在条索状性腺中显示。
J Pediatr. 1977 Apr;90(4):604-5. doi: 10.1016/s0022-3476(77)80378-8.
5
Pathogenetics of 45,X/46,XY gonadal mosaicism.45,X/46,XY性腺嵌合症的致病遗传学
Cytogenet Cell Genet. 1998;82(1-2):52-7. doi: 10.1159/000015064.
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Atypical gonadal dysgenesis. A clinical and cytogenetical report of three patients.非典型性腺发育不全。三例患者的临床及细胞遗传学报告。
J Obstet Gynaecol Br Commonw. 1973 Aug;80(8):735-44. doi: 10.1111/j.1471-0528.1973.tb16060.x.
7
[A rare case of gonadal dysgenesis with 45, X-46, X ring X mosaic--case report].[一例罕见的45,X-46,X环状X染色体嵌合型性腺发育不全病例报告]
Geburtshilfe Frauenheilkd. 1986 Jul;46(7):473-4. doi: 10.1055/s-2008-1036240.
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Mixed gonadal dysgenesis.混合性性腺发育不全
Acta Endocrinol Suppl (Copenh). 1975;197:1-39.
9
Hormonal and cytogenetic studies in phenotypically female patients with gonadal dysgenesis.
Int J Gynaecol Obstet. 1981 Apr;19(2):109-18. doi: 10.1016/0020-7292(81)90049-7.
10
Histopathologic study with cytogenetic correlation in 20 cases of gonadal dysgenesis.20例性腺发育不全的组织病理学研究及细胞遗传学相关性分析
Am J Clin Pathol. 1972 Apr;57(4):449-56. doi: 10.1093/ajcp/57.4.449.

本文引用的文献

1
Chromosome preparations of leukocytes cultured from human peripheral blood.从人外周血培养的白细胞的染色体标本制备。
Exp Cell Res. 1960 Sep;20:613-6. doi: 10.1016/0014-4827(60)90138-5.
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A sex-chromosome anomaly in a case of gonadal dysgenesis (Turner's syndrome).一例性腺发育不全(特纳综合征)患者的性染色体异常。
Lancet. 1959 Apr 4;1(7075):711-3. doi: 10.1016/s0140-6736(59)91893-8.
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Male pseudohermaphroditism: a hitherto undescribed form.男性假两性畸形:一种迄今未被描述的类型。
Br Med J. 1955 Sep 17;2(4941):709-12. doi: 10.1136/bmj.2.4941.709.
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The anatomy and histology of XO human embryos and fetuses.
Anat Rec. 1966 Jul;155(3):369-83. doi: 10.1002/ar.1091550309.
5
Leukocytes cultured from small inocula of whole blood and the preparation of metaphase chromosomes by treatment with hypotonic KCl.从小量全血接种物培养白细胞,并通过用低渗氯化钾处理制备中期染色体。
Stain Technol. 1965 Nov;40(6):333-8. doi: 10.3109/10520296509116440.
6
Germ cells in the ovaries of XO female infants.
Am J Clin Pathol. 1968 Apr;49(4):521-6. doi: 10.1093/ajcp/49.4.521.
7
Histopathologic study with cytogenetic correlation in 20 cases of gonadal dysgenesis.20例性腺发育不全的组织病理学研究及细胞遗传学相关性分析
Am J Clin Pathol. 1972 Apr;57(4):449-56. doi: 10.1093/ajcp/57.4.449.

卵巢发育不全的比较细胞遗传学和形态学研究。

Comparative cytogenetical and morphological studies in ovarian dysgenesis.

作者信息

Gaál M, László J, Bösze P

出版信息

J Clin Pathol. 1974 Dec;27(12):951-4. doi: 10.1136/jcp.27.12.951.

DOI:10.1136/jcp.27.12.951
PMID:4141709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC475561/
Abstract

In 14 cases of the Turner syndrome and pure gonadal dysgenesis streak gonads were studied histologically. In cases where the 46,XX line was unimpaired the blood vessels of the gonad showed severe degeneration in at least 30 to 50%. These streak gonads usually contained some of the characteristic ovarian elements as well as the vascular lesions. In gonosomal monosomy, on the other hand, a similar intensive vascular degeneration could not be found and the gonad consisted of indeterminate connective tissue. These observations are strong indications of a close correlation between karyotype and the histology of the streak gonad, which may supply further information on the manner and timing of the development of the streak gonad.

摘要

对14例特纳综合征和单纯性腺发育不全条索状性腺进行了组织学研究。在46,XX核型未受影响的病例中,性腺血管至少有30%至50%出现严重退变。这些条索状性腺通常含有一些特征性的卵巢成分以及血管病变。另一方面,在性染色体单体型中,未发现类似的严重血管退变,性腺由不确定的结缔组织组成。这些观察结果有力地表明核型与条索状性腺组织学之间存在密切关联,这可能为条索状性腺的发育方式和时间提供进一步信息。