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[主动脉起源的孤立性肾极动脉偶然结扎后可逆的“实验性”人类动脉高血压]

[Reversible "experimental" human arterial hypertension after fortuitous ligation of an isolated polar renal artery of aortic origin].

作者信息

Latour H, Ferrière M, Méry D, Reygroblet P, Bosc E, Baissus C, Chaptal P A

出版信息

Arch Mal Coeur Vaiss. 1977 Nov;70(11):1209-12.

PMID:414679
Abstract

During the course of an aorto-femoral bypass in a normotensive young man, an inferior polar artery arising low on the aorta, and supplying the right kidney, was ligated. The limited ischaemia (demonstrated by later arteriography) of the parenchyma at the pole of the kidney was responsible, during the following weeks, for severe hypertension with a raised level of circulating plasma renin, but one that was rapidly treatable. This finding, which was fortuitous but could be ranked as "experimental", demonstrates the important role of abnormal polar arteries and of the renal parenchyma in human arterial hypertension. Such may, for example, be the underlying disorder in cases of hypertension after the transplantation of a kidney with an "uncontrolled" polar artery arising from the aorta, for the so-called "pyelonephritic" hypertension in pregnant patients caused by defective blood supply in an inter-pyramidal artery and corresponding subcortical infarction of the kidney, and for curing hypertension in the adult when isolated polar arteries arising from the aorta and stenosed at their point of origin are reimplanted into the main renal artery.

摘要

在一名血压正常的年轻男性进行主动脉-股动脉搭桥手术过程中,结扎了一条起源于主动脉较低位置、供应右肾的下极动脉。术后数周,肾下极实质出现局限性缺血(后期血管造影证实),导致严重高血压,循环血浆肾素水平升高,但这种高血压易于迅速治疗。这一发现虽属偶然,但可视为“实验性”的,它证明了异常极动脉和肾实质在人类动脉高血压中所起的重要作用。例如,对于移植了一条由主动脉发出的“不受控制”的极动脉的肾脏后发生高血压的病例、对于妊娠患者因肾锥体间动脉血液供应不良及相应肾皮质下梗死所致的所谓“肾盂肾炎性”高血压病例,以及对于将起源于主动脉且在起始点狭窄的孤立极动脉重新植入肾主动脉后治愈成人高血压的情况,异常极动脉和肾实质可能是潜在的病因。

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