人类胎儿和儿童体内参与苯丙氨酸代谢的酶。
Enzymes involved in phenylalanine metabolism in the human foetus and child.
作者信息
McLean A, Marwick M J, Clayton B E
出版信息
J Clin Pathol. 1973 Sep;26(9):678-83. doi: 10.1136/jcp.26.9.678.
Abstract
The activities of phenylalanine p-hydroxylase, tyrosine: alpha-ketoglutarate and phenylalanine: pyruvate aminotransferases, and aromatic alpha-ketoacid reductase have been measured in liver biopsies obtained from children with a series of disorders other than phenylketonuria and from human foetuses aged 8.5 to 24 weeks. The importance of such a study in relation to the management of infants with hyperphenylalaninaemia and pregnant phenylketonuric women is discussed
摘要
已对从患有一系列除苯丙酮尿症之外的疾病的儿童以及8.5至24周龄的人类胎儿获取的肝脏活检样本中的苯丙氨酸对羟基化酶、酪氨酸：α-酮戊二酸转氨酶、苯丙氨酸：丙酮酸转氨酶和芳香族α-酮酸还原酶的活性进行了测定。讨论了此类研究对于高苯丙氨酸血症婴儿和患有苯丙酮尿症的孕妇的管理的重要性。
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本文引用的文献
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The amino-acid pattern in human foetal and maternal plasma at delivery.分娩时人胎儿和母体血浆中的氨基酸模式。
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Reduction of phenylpyruvic acids to phenyllactic acids in mammalian tissues.哺乳动物组织中苯丙酮酸还原为苯乳酸。
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Phenylalaninaemia or classical phenylketonuria (PKU)?苯丙酮尿症还是经典型苯丙酮尿症（PKU）？
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Reduction of aromatic alpha-keto acids by lactic dehydrogenase isozymes and aromatic alpha-keto acid reductase.乳酸脱氢酶同工酶和芳香族α-酮酸还原酶对芳香族α-酮酸的还原作用。
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