与比格犬肝脏孵育产生的氧合炔诺酮衍生物。结构、合成及生物活性。 - Suppr

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超能文献

Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity.

作者信息

Cook C E, Dickey M C, Christensen H D

出版信息

Drug Metab Dispos. 1974 Jan-Feb;2(1):58-64.

PMID:4150135

Abstract

摘要

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Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity.与比格犬肝脏孵育产生的氧合炔诺酮衍生物。结构、合成及生物活性。

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引用本文的文献

Structure elucidation of two isomeric steroids: photolytical and thermal reaction products from norethisterone studied by two-dimensional nuclear magnetic resonance.两种异构甾体的结构解析：通过二维核磁共振研究炔诺酮的光解和热反应产物

Pharm Weekbl Sci. 1985 Oct 25;7(5):202-7. doi: 10.1007/BF02307577.

Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol.炔诺酮或炔雌醇导致大鼠肝脏细胞色素P - 450减少。

Biochem J. 1977 Jul 15;166(1):57-64. doi: 10.1042/bj1660057.

Metabolic activation of acetylenic substituents to derivatives in the rat causing the loss of hepatic cytochrome P-450 and haem.大鼠体内乙炔取代基代谢活化为衍生物，导致肝细胞色素P-450和血红素丧失。

Biochem J. 1978 Sep 15;174(3):853-61. doi: 10.1042/bj1740853.

Structural modifications in contraceptive steroids altering their metabolism and toxicity.改变代谢和毒性的避孕甾体的结构修饰。

Arch Toxicol. 1977 Dec 30;39(1-2):13-9. doi: 10.1007/BF00343271.

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