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对维生素B12缺乏的狒狒正中神经的 teased纤维研究

A teased-fibre study of the median nerves of vitamin B12-depleted baboons.

作者信息

Knowles J F

出版信息

J Anat. 1978 Feb;125(Pt 2):223-30.

Abstract

Isolated nerve fibres of the median nerve of normal baboons and baboons kept on diets deficient in vitamin B12, and supplemented with potassium cyanide and potassium thiocyanate injections, were examined by the teased-fibre technique. Regression lines of internodal length on fibre diameter were obtained. Small differences between the groups were apparent but were of uncertain significance. There was occasional evidence of segmental demyelination and Wallerian degeneration but this was not characteristic of any particular group.

摘要

采用 teased-fibre 技术检查了正常狒狒以及食用缺乏维生素 B12 饮食并补充氰化钾和硫氰酸钾注射剂的狒狒正中神经的分离神经纤维。获得了节间长度与纤维直径的回归线。各实验组之间存在微小差异,但意义不明确。偶尔有节段性脱髓鞘和华勒氏变性的证据,但这并非任何特定实验组所特有。

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本文引用的文献

1
Growth changes in the myelin sheath of peripheral nerve fibres in fishes.鱼类外周神经纤维髓鞘的生长变化
Proc R Soc Lond B Biol Sci. 1955 Mar 15;143(912):380-91. doi: 10.1098/rspb.1955.0018.
3
Clinical and pathological study of ischaemic neuropathy.缺血性神经病的临床与病理研究
J Neurol Neurosurg Psychiatry. 1967 Jun;30(3):215-26. doi: 10.1136/jnnp.30.3.215.
6
Changes due to age in internodal length in the sural nerve in man.人类腓肠神经节间长度随年龄的变化。
J Neurol Neurosurg Psychiatry. 1966 Feb;29(1):40-4. doi: 10.1136/jnnp.29.1.40.
9
Vitamin B12 deficiency in captive monkeys and its effect on the nervous system and the blood.
Lab Anim. 1970 Apr;4(1):1-12. doi: 10.1258/002367770781036526.

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