灰色链霉菌中的基因重组
Genetic recombination in Streptomyces griseus.
作者信息
Parag Y
出版信息
J Bacteriol. 1978 Feb;133(2):1027-31. doi: 10.1128/jb.133.2.1027-1031.1978.
Abstract
Low-frequency (10(-6)) genetic recombination was observed in a cephamycin-producing strain of Streptomyces griseus. The recombinants were predominantly heteroclones. Heteroclone analysis was performed involving four heteroclones of one cross. In 100 mutants correlation was found between the type of auxotrophy and the level of antibiotic activity. A cross of this strain with a streptomycin-producing strain of S. griesus is described.
摘要
在灰色链霉菌的一个头孢霉素生产菌株中观察到低频（10⁻⁶）基因重组。重组体主要是异核体。对一个杂交组合的四个异核体进行了异核体分析。在100个突变体中，发现营养缺陷型的类型与抗生素活性水平之间存在相关性。描述了该菌株与灰色链霉菌的一个链霉素生产菌株的杂交。
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