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[采用125碘光子吸收法对慢性血液透析期间骨矿物质含量进行长期观察(作者译)]

[Bone mineral content during chronic hemodialysis long term observation by 125-i photonabsorptiometry (author's transl)].

作者信息

Kuhlencordt F, Ringe J D

出版信息

Klin Wochenschr. 1978 Jan 15;56(2):75-9. doi: 10.1007/BF01480087.

Abstract

40 out of 98 patients on chronic haemodialysis show an obviously lowered bone mineral content of the radius (mean -20.4%), 51 patients attain values in the normal range (mean -1%) and 7 subjects slightly increased values (mean +10.9%). A bone mineral loss of 2.5% could be found after long-term observations of this parameter between 6 to 30 months (mean observation period: 15 months). In general a progressive loss of the bone mineral content may be noticed with an increased duration of haemodialysis. This tendency is more distinct after the 40th year of life because of the simultaneous age-depending physiological decrease of bone mass. Abruptly occurring mineral losses of the skeleton may be due to a high incretion of parathyroid hormone and possibly require subtotal parathyroidectomy.

摘要

98例慢性血液透析患者中,40例桡骨骨矿物质含量明显降低(平均降低20.4%),51例患者的值在正常范围内(平均降低1%),7例患者的值略有升高(平均升高10.9%)。对该参数进行6至30个月的长期观察后发现,骨矿物质流失率为2.5%(平均观察期:15个月)。一般来说,随着血液透析时间的延长,骨矿物质含量会逐渐流失。由于同时存在与年龄相关的生理性骨量减少,这种趋势在40岁以后更为明显。骨骼矿物质的突然流失可能是由于甲状旁腺激素分泌过多,可能需要进行甲状旁腺次全切除术。

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