Castelli W A, Nasjleti C E, Caffesse R E, Diaz-Perez R
Oral Surg Oral Med Oral Pathol. 1978 Feb;45(2):179-85. doi: 10.1016/0030-4220(78)90083-x.
Silk, cotton, and nylon suture materials were implanted in the tunica propria of the gingiva in seven adult rhesus monkeys. The histologie study of twenty-four biopsy specimens indicated that there was neither an increase in the vascular permeability nor a leukocytic margination and migration into the tissues adjacent to the suture materials. However, there was a variable histiocytic reaction, with multinucleated cell formation. This reaction was quite intense with cotton, less intense with silk, and practically absent with nylon. The greater cellular response to cotton was probably due to its more active capacity for modifying the internal biologic medium of the gingvia.
将丝绸、棉花和尼龙缝合材料植入7只成年恒河猴牙龈的固有层中。对24个活检标本的组织学研究表明，血管通透性没有增加，也没有白细胞靠边和迁移到缝合材料附近的组织中。然而，有不同程度的组织细胞反应，并形成了多核细胞。这种反应在棉花植入时相当强烈，在丝绸植入时较弱，而在尼龙植入时几乎没有。对棉花产生更大的细胞反应可能是由于其改变牙龈内部生物介质的能力更强。
