Arístegui J, Juan S, Saitúa G, Hernández M
An Esp Pediatr. 1977 Nov;10(11):835-42.
We tried to evaluate the utility of the Limulus Test in the diagnosis of acute meningitis. The study was made in 60 patients divided in three groups: Group A, formed by 37 children affected by purulent meningitis of known etiology; Group B, formed by 10 children affected by purulent meningitis of unknown etiology; Group C, formed by 13 children with viral meningitis. The results were compared with a control group (Group D), of 10 healthy children. The results correlated with the etiology, the cuantitative count of germs/ml. in C.S.F. and the clinical evolution. The results indicated that the Test is a rapid, simple and useful tool for the detection of endotoxin in the C.S.F. of purulent meningitis caused by Gram negative germs.
我们试图评估鲎试剂检测在急性脑膜炎诊断中的效用。该研究纳入了60名患者,分为三组:A组由37名已知病因的化脓性脑膜炎患儿组成;B组由10名病因不明的化脓性脑膜炎患儿组成;C组由13名病毒性脑膜炎患儿组成。结果与10名健康儿童的对照组(D组)进行比较。结果与病因、脑脊液中每毫升细菌的定量计数以及临床病程相关。结果表明,该检测是一种快速、简单且有用的工具,可用于检测由革兰氏阴性菌引起的化脓性脑膜炎脑脊液中的内毒素。