Trust T J, Chipman D C
Antimicrob Agents Chemother. 1974 Oct;6(4):379-86. doi: 10.1128/AAC.6.4.379.
The antibacterial activity of eight products marketed for the therapy and prophylaxis of diseases of ornamental fishes was tested. The products contained erythromycin, neomycin, a nitrofuran, penicillin, sulfa compounds, streptomycin, or tetracycline. When used at the concentration recommended by the manufacturer, the products failed to inhibit the growth of bacterial species known to be potential pathogens of ornamental fishes and failed to reduce significantly the bacterial numbers in water containing fish. Concentrations of the products that were bacteriostatic were markedly higher than the in-use concentration recommended by the manufacturer. The danger presented by the unrestricted availability of antibiotic compounds frequently used in the treatment of human and animal disease is discussed.
对八种用于观赏鱼疾病治疗和预防的市售产品的抗菌活性进行了测试。这些产品含有红霉素、新霉素、一种硝基呋喃、青霉素、磺胺类化合物、链霉素或四环素。当按照制造商推荐的浓度使用时，这些产品未能抑制已知为观赏鱼潜在病原体的细菌种类的生长，也未能显著减少养鱼水中的细菌数量。具有抑菌作用的产品浓度明显高于制造商推荐的使用浓度。文中讨论了常用于治疗人类和动物疾病的抗生素化合物不受限制地可得所带来的危险。
