盐酸、氯化铵和碳酸氢铵给药对人体尿素和铵排泄的影响。

The effects of administrations of HCl, NH4Cl and NH4HCO3 on the excretion of urea and ammonium in man.

作者信息

Fine A, Carlyle J E, Bourke E

出版信息

Eur J Clin Invest. 1977 Dec;7(6):587-9. doi: 10.1111/j.1365-2362.1977.tb01655.x.

DOI:10.1111/j.1365-2362.1977.tb01655.x

Abstract

In man, HCl acidosis reduces blood and urinary urea with a concomitant rise in ammonium (NH4+) excretion. Significantly less urea is excreted following NH4Cl administration than following equimolar ingestion of NH4 HCO3. The results of these alterations in nitrogen excretion are interpreted in terms of bicarbonate utilization and production.

摘要

在人类中，盐酸酸中毒会降低血液和尿液中的尿素含量，同时铵（NH4+）排泄量增加。给予氯化铵后排出的尿素明显少于给予等摩尔量碳酸氢铵后的情况。这些氮排泄变化的结果是根据碳酸氢盐的利用和产生来解释的。