静脉注射促甲状腺激素释放激素（TRH）可增强乙酰胆碱（ACh）对大鼠皮层神经元的兴奋作用。
Intravenous thyrotropin releasing hormone (TRH) enhances the excitatory actions of acetylcholine (ACh) on rat cortical neurons.
作者信息
Yarbrough G G, Singh D K
出版信息
Experientia. 1978 Mar 15;34(3):390. doi: 10.1007/BF01923054.
PMID:415897
Abstract
I.v. administered TRH (1.25--10 mg/kg) enhanced the excitatory actions of iontophoretically applied ACh on spontaneously active cerebral cortical neurons of pentobarbital-anaesthetized rats. These observations are consistent with the hypothesis of a cholinergic-link in the anti-anaesthetic actions of exogenously administered TRH.
摘要
静脉注射促甲状腺激素释放激素（TRH，1.25 - 10毫克/千克）增强了离子导入法施加乙酰胆碱（ACh）对戊巴比妥麻醉大鼠自发活动的大脑皮质神经元的兴奋作用。这些观察结果与外源性给予TRH的抗麻醉作用中存在胆碱能联系的假设一致。
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