Abel C A, Grey H M
Science. 1967 Jun 23;156(3782):1609-10. doi: 10.1126/science.156.3782.1609.
The carboxy-terminal amino acids of alpha-and micro-chains from human immunoglobulins and alpha-chains from mouse immunoglobulins have been determined by carboxypeptidase digestion and hydrazinolysis. The data suggest the following carboxy-terminal sequences: human micro: Ala-Gly-Thr-Cys-TyrCOOH; human alpha: Thr-Cys-TyrCOOH; murine alpha: (Ileu, Cys)-TyrCOOH.
通过羧肽酶消化和肼解测定了人免疫球蛋白α链和μ链以及小鼠免疫球蛋白α链的羧基末端氨基酸。数据表明以下羧基末端序列:人μ链:丙氨酸-甘氨酸-苏氨酸-半胱氨酸-酪氨酸-COOH;人α链:苏氨酸-半胱氨酸-酪氨酸-COOH;小鼠α链:(异亮氨酸,半胱氨酸)-酪氨酸-COOH。