Wood B P, Katzberg R W
AJR Am J Roentgenol. 1978 Apr;130(4):747-50. doi: 10.2214/ajr.130.4.747.
Although successful treatment of meconium ileus with Gastrografin enema has been attributed to the hypertonicity of this material, Tween 80, present in a 0.75% concentration, may be its most effective component. Tween 80 acts as a surface-active substance and stool emulsifier. An enema solution of 1%-2% Tween 80 and isotonic sodium diatrizoate has been effective in the relief of meconium or fecal mass obstruction in infants and children.
尽管泛影葡胺灌肠成功治疗胎粪性肠梗阻被认为是由于该物质的高渗性，但浓度为0.75%的吐温80可能是其最有效的成分。吐温80作为一种表面活性物质和粪便乳化剂。1%-2%吐温80与等渗泛影酸钠的灌肠溶液已有效缓解婴幼儿和儿童的胎粪或粪块梗阻。
