Görög P, Kovács I B
Arthritis Rheum. 1978 Mar;21(2):256-9. doi: 10.1002/art.1780210214.
A marked increase in platelet count was observed in adjuvant-induced polyarthritic rats. Elevation of platelet count was still significant 3 months after onset of disease. Increased number and larger size of platelets reflect an increase in the rate of platelet production. By means of the platelet-count ratio technique, circulating platelet aggregates were demonstrated in rats with severe arthritis. Aspirin treatment prevented thrombocytosis and formation of platelet aggregates.
在佐剂诱导的多关节炎大鼠中观察到血小板计数显著增加。疾病发作3个月后血小板计数仍显著升高。血小板数量增加和体积增大反映了血小板生成速率的增加。通过血小板计数比技术，在重症关节炎大鼠中证实了循环血小板聚集体的存在。阿司匹林治疗可预防血小板增多症和血小板聚集体的形成。
