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获得性因子 VIII 抗体：进一步的免疫学和电泳研究。

Acquired factor 8 antibodies: further immunologic and electrophoretic studies.

作者信息

Shapiro S S, Carroll K S

出版信息

Science. 1968 May 17;160(3829):786-7. doi: 10.1126/science.160.3829.786.

DOI:10.1126/science.160.3829.786
PMID:4171540
Abstract

Seven new cases of acquired inhibitors of Factor VIII have been typed immunologically as (gamma2kappa2) antibodies. Electrophoretic mobility on starch block of a combined group of 13 such antibodies is considerably more rapid than that of the bulk of immunoglobulin G.

摘要

7例新获得性凝血因子VIII抑制剂经免疫分型为（γ2κ2）抗体。13例这类抗体的混合组在淀粉块上的电泳迁移率明显快于大部分免疫球蛋白G。

相似文献

1
Acquired factor 8 antibodies: further immunologic and electrophoretic studies.获得性因子 VIII 抗体：进一步的免疫学和电泳研究。
Science. 1968 May 17;160(3829):786-7. doi: 10.1126/science.160.3829.786.
2
Antibody nature of an AHG (factor 8) inhibitor.抗人球蛋白（因子8）抑制剂的抗体性质
J Pediatr. 1968 Mar;72(3):325-31. doi: 10.1016/s0022-3476(68)80203-3.
3
[Factor VIII inhibitor-caused hemophilia].
Orv Hetil. 1977 Sep 4;118(36):2145-9.
4
[Development of inhibitors following long-term substitution of human antihemophilia globulin in severe hemophilia].
Klin Wochenschr. 1967 Jun 15;45(12):630-3. doi: 10.1007/BF01745636.
5
Inhibitors in haemophilia.
Bibl Haematol. 1970;34:125-34. doi: 10.1159/000384904.
6
The rapid development of an IgM inhibitor of porcine factor VIII in a patient with acquired haemophilia.一名获得性血友病患者中猪源因子VIII的IgM抑制剂的快速发展。
Br J Haematol. 1990 Jul;75(3):434-6. doi: 10.1111/j.1365-2141.1990.tb04361.x.
7
Immunological analysis of acquired factor VIII inhibitor in a case with immunologic disorder.一例免疫紊乱患者获得性凝血因子VIII抑制物的免疫学分析
Acta Haematol. 1991;85(3):153-5. doi: 10.1159/000204879.
8
[Inhibitors (antibodies) directed against factor VIII in hemophilia A (author's transl)].
Ther Umsch. 1979 Apr;36(4):326-9.
9
[Determination of coagulation factor VIII inhibitors].
Z Gesamte Inn Med. 1980 Apr 15;35(8):330-6.
10
The immunologic character of acquired inhibitors of antihemophilic globulin (factor 8) and the kinetics of their interaction with factor 8.获得性抗血友病球蛋白（因子VIII）抑制物的免疫学特性及其与因子VIII相互作用的动力学
J Clin Invest. 1967 Feb;46(2):147-56. doi: 10.1172/JCI105517.

引用本文的文献

1
Serum immunoglobulins in patients with congenital coagulation defects and their relatives.
Z Kinderheilkd. 1971;109(3):199-210. doi: 10.1007/BF00442269.
2
[Factor 8 in a female patient with haemophilia A during pregnancy].[一名患甲型血友病的女性患者孕期的凝血因子Ⅷ情况]
Arch Gynakol. 1971 Oct 28;210(4):386-94. doi: 10.1007/BF01628218.
3
Factor V anticoagulants: clinical, biochemical, and immunological observations.凝血因子V抗凝剂：临床、生化及免疫学观察
J Clin Invest. 1970 Aug;49(8):1578-88. doi: 10.1172/JCI106375.
4
Enzyme-linked immunosorbent assay for immunoglobulin G subclass antibodies specific for enterobacterial Re core glycolipid in healthy individuals and in patients infected by gram-negative bacteria.健康个体及革兰氏阴性菌感染患者中针对肠杆菌属Re核心糖脂特异性免疫球蛋白G亚类抗体的酶联免疫吸附测定。
J Clin Microbiol. 1988 May;26(5):857-62. doi: 10.1128/jcm.26.5.857-862.1988.
5
Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.韦格纳肉芽肿病及临床相关疾病患者中抗中性粒细胞胞浆自身抗体（ANCA）的IgG1和IgG4亚类占优势。
Clin Exp Immunol. 1991 Mar;83(3):379-86. doi: 10.1111/j.1365-2249.1991.tb05647.x.