Drill V A, Golway P L
J Natl Cancer Inst. 1978 May;60(5):1169-70. doi: 10.1093/jnci/60.5.1169.
The oral contraceptive combination of ethynodiol diacetate with ethinyl estradiol (Demulen) was given cyclically to 48 female rhesus monkeys for 5 years. Doses employed were 1, 10, and 50 times the human dose. Treatment did not induce palpable breast nodules, and there were no deaths from mammary gland cancer.
将乙炔雌二醇与双醋炔诺醇的口服避孕药组合（Demulen）以周期性方式给予48只雌性恒河猴，持续5年。所使用的剂量分别为人用剂量的1倍、10倍和50倍。治疗未诱发可触及的乳腺结节，也没有因乳腺癌死亡的情况。
