Dogon I L, Heeley J D
Oral Surg Oral Med Oral Pathol. 1978 Apr;45(4):503-15. doi: 10.1016/0030-4220(78)90030-0.
A fluoroalkyl cyanoacrylate is shown to be a very effective hemostatic agent in routine extractions in rhesus monkeys. Clinical and histologic observations of the healing sockets at selected intervals revealed uneventful healing, even when the tissue adhesive was placed directly against the alveolar bone within the extraction socket. The quantity, quality, and rate of bone replacement were not different between the experimental and control groups. When polymerized cyanoacrylate is entrapped within the connective tissue above the healing socket, it is effectively removed by normal tissue phagocytes.
一种氟烷基氰基丙烯酸酯在恒河猴的常规拔牙术中被证明是一种非常有效的止血剂。在选定的时间间隔对拔牙窝愈合情况进行的临床和组织学观察显示,即使将组织粘合剂直接放置在拔牙窝内的牙槽骨上,愈合过程也很顺利。实验组和对照组在骨替代的数量、质量和速度方面没有差异。当聚合的氰基丙烯酸酯被困在拔牙窝上方的结缔组织中时,它会被正常组织中的吞噬细胞有效清除。