Barbakow F H, Austin J C, Cleaton-Jones P E
Oral Surg Oral Med Oral Pathol. 1978 Apr;45(4):621-8. doi: 10.1016/0030-4220(78)90045-2.
Central incisors in the vervet monkey were extracted, endodontically treated, and replanted into their original sockets after immersion in a 2 per cent acidulated sodium fluoride solution (pH 5.5) for 30 minutes. Histologic examination at 1, 2, 4, and 8 weeks postoperatively showed that by the second week resorption had taken place and that ankylosis, first seen by the fourth week, along both the buccal and palatal root surfaces, was well established by the eighth week. Under the conditions of the study, pretreatment of the tooth roots with 2 per cent acidulated sodium fluoride did not reduce root resorption and ankylosis.
将绿猴的中切牙拔除、进行根管治疗,然后在2%的酸化氟化钠溶液(pH 5.5)中浸泡30分钟后再植回原牙槽窝。术后1周、2周、4周和8周进行组织学检查,结果显示到第2周时已发生吸收,到第4周时首次在颊侧和腭侧牙根表面出现的骨性粘连,到第8周时已完全形成。在本研究条件下,用2%的酸化氟化钠对牙根进行预处理并不能减少牙根吸收和骨性粘连。