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普通狨猴(绢毛猴)在生殖研究中的应用。

Use of the common marmoset, Callithrix jacchus, in reproductive research.

作者信息

Hearn J P, Abbott D H, Chambers P C, Hodges J K, Lunn S F

出版信息

Primates Med. 1978;10:40-9.

PMID:417331
Abstract

A self-sustaining colony of common marmosets, Callithrix jacchus, was established for reproductive research. Methods of management were developed to ensure optimal breeding conditions for marmosets in captivity. Studies of the reproductive biology and endocrinology of this species suggest that the common marmoset may be a suitable model for the human in certain aspects of the ovarian cycle, pregnancy, puberty and the hypothalamic and pituitary control of luteinizing hormone secretion. The rapid rate of reproduction of C. jacchus in captivity allows a relatively large colony to be maintained at moderate cost and also makes this species a most suitable laboratory primate for longer term studies of the safety and efficacy of new contraceptive methods.

摘要

为了进行生殖研究,建立了一个普通狨猴(Callithrix jacchus)的自我维持群体。开发了管理方法,以确保圈养条件下狨猴的最佳繁殖条件。对该物种生殖生物学和内分泌学的研究表明,在卵巢周期、怀孕、青春期以及黄体生成素分泌的下丘脑和垂体控制的某些方面,普通狨猴可能是人类的合适模型。圈养条件下普通狨猴的快速繁殖率使得能够以适度成本维持相对较大的群体,这也使该物种成为研究新避孕方法安全性和有效性的长期研究中最合适的实验室灵长类动物。

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