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Reaction of drugs with microsomal liver hydroxylase: its influence on drug action.

作者信息

Remmer H, Estabrook R W, Schenkman J, Greim H

出版信息

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;259(2):98-116. doi: 10.1007/BF00537741.

DOI:10.1007/BF00537741
PMID:4173846
Abstract
摘要

相似文献

1
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action.药物与肝微粒体羟化酶的反应：其对药物作用的影响。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;259(2):98-116. doi: 10.1007/BF00537741.
2
[Spectral properties of cytochrome P450 following induction with phenobarbital, benzopyrene and methylcholanthrene].[苯巴比妥、苯并芘和甲基胆蒽诱导后细胞色素P450的光谱特性]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):189-90.
3
Effect of partial hepatectomy of the responsiveness of microsomal enzymes and cytochrome P-450 to phenobarbital or 3-methylcholanthrene.部分肝切除对微粒体酶及细胞色素P - 450对苯巴比妥或3 - 甲基胆蒽反应性的影响。
Biochem Pharmacol. 1968 Sep;17(9):1769-78. doi: 10.1016/0006-2952(68)90092-0.
4
Induction of microsomal hydroxylase: involvement of a second factor besides cytochrome P-450.微粒体羟化酶的诱导：除细胞色素P - 450外第二种因子的参与。
Hoppe Seylers Z Physiol Chem. 1968 Nov;349(11):1621-4.
5
[Hydroxylase activity and hemoprotein content of microsomes from rabbit liver].[兔肝微粒体的羟化酶活性和血红素蛋白含量]
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6
Sex-related differences in drug metabolism.
Drug Metab Rev. 1974;3(1):1-32. doi: 10.3109/03602537408993737.
7
Different effect of aflatoxin on the induction of tryptophan oxygenase and of microsomal drug-hydroxylase system.
J Biochem. 1970 Oct;68(4):589-92. doi: 10.1093/oxfordjournals.jbchem.a129391.
8
[Completion of the induction of microsomal enzymes in the rabbit liver].[兔肝脏微粒体酶诱导作用的完成]
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Spectral studies of drug interaction with hepatic microsomal cytochrome.药物与肝微粒体细胞色素相互作用的光谱研究
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10
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes.
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引用本文的文献

1
Induction of drug metabolising enzymes: pharmacokinetic and toxicological consequences in humans.药物代谢酶的诱导：对人体药代动力学和毒理学的影响
Clin Pharmacokinet. 2000 Jun;38(6):493-504. doi: 10.2165/00003088-200038060-00003.
2
[Drug uptake and catabolism in the fetal period].[胎儿期的药物摄取与分解代谢]
Arch Gynakol. 1971 Jun 4;211(1):112-33. doi: 10.1007/BF00682858.
3
[Effect of carbon tetrachloride on endoplasmic enzymes in rat liver].[四氯化碳对大鼠肝脏内质网酶的影响]

本文引用的文献

1
Acetylcholinesterase. X. Mechanism of the catalysis of acylation reactions.乙酰胆碱酯酶。十、酰化反应的催化机制。
J Biol Chem. 1950 Oct;186(2):781-90.
2
[INCREASE IN DRUG OXIDIZING ENZYME ACTIVITY WITH TOLBUTAMIDE].[甲苯磺丁脲导致药物氧化酶活性增加]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1964 Oct 2;249:71-84. doi: 10.1007/BF00246370.
3
DRUG INTERACTIONS IN MAN. I. LOWERING EFFECT OF PHENOBARBITAL ON PLASMA LEVELS OF BISHYDROXYCOUMARIN (DICUMAROL) AND DIPHENYLHYDANTOIN (DILANTIN).人体中的药物相互作用。I. 苯巴比妥对双香豆素（双香豆素）和苯妥英（大仑丁）血浆水平的降低作用。
Arch Toxikol. 1971;28(1):1-11.
4
The effect of magnesium ions on the dimethylaniline oxidation rate and electron transfer in liver microsomal fraction.镁离子对肝微粒体部分中二甲苯胺氧化速率及电子转移的影响。
Biochem J. 1973 Oct;136(2):371-9. doi: 10.1042/bj1360371.
5
Mechanism of inhibition by carbonyl cyanide m-chlorophenylhydrazone and sodium deoxycholate of cytochrome P-450-catalysed hepatic microsomal drug metabolism.间氯苯腙羰基氰化物和脱氧胆酸钠对细胞色素P-450催化的肝微粒体药物代谢的抑制机制。
Biochem J. 1976 Oct 15;160(1):75-83. doi: 10.1042/bj1600075.
Clin Pharmacol Ther. 1965 Jul-Aug;6:420-9. doi: 10.1002/cpt196564420.
4
AN ELECTRON SPIN RESONANCE STUDY OF SOME HEMOPROTEINS.一些血红蛋白的电子自旋共振研究
J Biol Chem. 1965 Jun;240:2654-9.
5
MORPHOLOGICAL CHANGES IN THE LIVER ACCOMPANYING STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYME ACTIVITY BY PHENOBARBITAL, CHLORDANE, BENZPYRENE OR METHYL-CHOLANTHRENE IN RATS.苯巴比妥、氯丹、苯并芘或甲基胆蒽刺激大鼠微粒体药物代谢酶活性时肝脏的形态学变化
J Pharmacol Exp Ther. 1965 Jan;147:112-9.
6
[ACCELERATED DRUG DEGRADATION BY ENZYME INDUCTION IN DOGS AFTER TREATMENT WITH PHENOBARBITAL].[苯巴比妥治疗后犬体内酶诱导引起的药物加速降解]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1964 Jul 28;247:522-43. doi: 10.1007/BF00329899.
7
PHOTOCHEMICAL ACTION SPECTRUM OF THE TERMINAL OXIDASE OF MIXED FUNCTION OXIDASE SYSTEMS.混合功能氧化酶系统末端氧化酶的光化学作用光谱
Science. 1965 Jan 22;147(3656):400-2. doi: 10.1126/science.147.3656.400.
8
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES.肝微粒体的一氧化碳结合色素。II. 增溶、纯化及性质
J Biol Chem. 1964 Jul;239:2379-85.
9
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.肝微粒体的一氧化碳结合色素。I. 其血红蛋白性质的证据。
J Biol Chem. 1964 Jul;239:2370-8.
10
INSUFFICIENT PARAPHYDROXYLATION AS A CAUSE OF DIPHENYLHYDANTOIN TOXICITY.羟化不足作为苯妥英钠毒性的一个原因
Neurology. 1964 Jun;14:542-8. doi: 10.1212/wnl.14.6.542.