培养时间对17-β雌二醇刺激腺垂体激素释放的影响（作者译）
[Effect of time in culture on the stimulatory effect of 17-beta estradiol on adenohypophyseal hormone release (author's transl)].
作者信息
Lagacé L, Labrie F
出版信息
Ann Endocrinol (Paris). 1977;38(6):373-4.
Secretion of LH, FSH, TSH and prolactin was studied in rat anterior pituitary cells in primary culture. Basal LH release, LH cell content and LH responsiveness to LHRH decreased with a half-life of 4 days. Basal FSH decreased only 20% up to 20 days thus indicating the relative independence of FSH secretion compared to that of LH. The stimulatory effect of 17-beta estradiol on LH and FSH secretion was higher during the first days in culture. The stimulatory effect of 17-beta estradiol on prolactin secretion did however remain maximal up to 20 days.
对原代培养的大鼠垂体前叶细胞中促黄体生成素（LH）、促卵泡生成素（FSH）、促甲状腺激素（TSH）和催乳素的分泌进行了研究。基础LH释放量、LH细胞含量以及LH对促性腺激素释放激素（LHRH）的反应性以4天的半衰期下降。基础FSH在长达20天的时间里仅下降了20%，这表明与LH相比，FSH分泌具有相对独立性。在培养的最初几天，17-β雌二醇对LH和FSH分泌的刺激作用更强。然而，17-β雌二醇对催乳素分泌的刺激作用在长达20天的时间里一直保持最大。
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