Brillinger G U, Heberle W, Weber B, Achenbach H
Arch Microbiol. 1978 Mar;116(3):245-52. doi: 10.1007/BF00417847.
In the course of a screening for new metabolites from fungi we isolated a substance with antimicrobial activity from cultures of Aspergillus duricaulis (CBS 481.65) (Tü 679). It was antagonized by putrescine, spermidine, spermine, arginine, citrulline, lysine, ornithine, in higher concentration by aspraagine and glutamine too. The effect of ethylenediaminetetraacetate on the susceptibility of Streptomyces viridochromogenes (Tü 57) and Bacillus subtilis ATCC 6051 to this antibiotic has been studied. The substance was characterized and identified as cyclopaldic acid.
在对真菌新代谢产物的筛选过程中，我们从硬柄曲霉（CBS 481.65）（Tü 679）的培养物中分离出一种具有抗菌活性的物质。它受到腐胺、亚精胺、精胺、精氨酸、瓜氨酸、赖氨酸、鸟氨酸的拮抗作用，天冬酰胺和谷氨酰胺在较高浓度时也有拮抗作用。研究了乙二胺四乙酸对绿色产色链霉菌（Tü 57）和枯草芽孢杆菌ATCC 6051对这种抗生素敏感性的影响。该物质经表征和鉴定为环杷地酸。
