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[用炎性肉芽肿的一个组分处理后小鼠对单核细胞增生李斯特菌的抵抗力增强]

[Increased resistance in mice to Listeria monocytogenes after treatment with a fraction from an inflammatory granuloma].

作者信息

Fauve R M, Hevin B

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Dec 19;285(16):1589-92.

PMID:417840
Abstract

The multiplication of Listeria monocytogenes in the spleen was decreased between the 3rd and the 11th day following the inflammatory reaction induced in Mice by subcutaneous implantation of talc embedded in a calcium phosphate gel into the dorsal area. A similar activity was observed after injection of SO4 (NH4)2 fractionated extracts from granuloma. The major activities were found in the 33% saturation precipitate and in the 80% saturation supernatant.

摘要

在小鼠背部皮下植入磷酸钙凝胶包埋的滑石粉诱导炎症反应后的第3天至第11天,脾脏中单核细胞增生李斯特菌的增殖减少。注射肉芽肿的硫酸铵分级分离提取物后也观察到类似的活性。主要活性存在于33%饱和度沉淀物和80%饱和度上清液中。

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引用本文的文献

1
Immunostimulatory mouse granuloma protein.免疫刺激小鼠肉芽肿蛋白
Proc Natl Acad Sci U S A. 1983 Oct;80(20):6395-8. doi: 10.1073/pnas.80.20.6395.

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