Rabinowitz D, McKenna T J, Benveniste R
Isr J Med Sci. 1978 Feb;14(2):256-60.
We studied the effects of a dopaminergic agonist, 2-chloro-6-methyl-ergoline-8-beta-acetonitrile methanesulfonate (LERGOTRILE mesylate), on the pituitary and adrenal function of five normal women. No changes were observed in basal serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), growth hormone (GH) and cortisol levels, in LH and FSH levels after luteinizing hormone-releasing hormone (LH-RH) stimulation, or in GH and cortisol levels during insulin-induced hypoglycemia. Lergotrile treatment produced a fall in basal prolactin and thyrotropin (TSH) levels and there was dissociation in the responses of the women to thyrotropin-releasing hormone: attenuation of TSH release, but retention of prolactin release.
我们研究了多巴胺能激动剂2-氯-6-甲基麦角灵-8-β-乙腈甲磺酸盐（甲磺酸麦角腈）对五名正常女性垂体和肾上腺功能的影响。基础血清促黄体生成素（LH）、促卵泡生成素（FSH）、生长激素（GH）和皮质醇水平，促黄体生成素释放激素（LH-RH）刺激后的LH和FSH水平，或胰岛素诱导低血糖期间的GH和皮质醇水平均未观察到变化。麦角腈治疗使基础催乳素和促甲状腺激素（TSH）水平下降，并且这些女性对促甲状腺激素释放激素的反应存在分离：TSH释放减弱，但催乳素释放保留。
