Cooper M H, Beal J A
J Comp Neurol. 1978 Jul 1;180(1):17-41. doi: 10.1002/cne.901800103.
Two types of neurons, projection and intrinsic, previously identified in Golgi preparations of the adult monkey (Macaca mulatta) basilar pontine gray (Cooper and Fox, '76) were observed electronmicroscopically in Macaca mulatta and the squirrel monkey Saimiri sciureus. The cell body of the projection neuron measures up to 37 micrometer and its cytoplasm is rich in organelles. The Goli apparatus, ribosomes, and mitochondria are disposed around the nucleus, while rough endoplasmic reticulum though abundant is usually confined to one half of the cell body. The cell body of the intrinsic neuron measures less than 20 micrometer and its cytoplasm displays prominent ribosomes, but a paucity of other organelles. Five types of synaptic profiles have been identified in the neuropil of the basilar pons; one measures up to 5 micrometer and the rest 2 micrometer or less. They are: (1) a large profile (MSV) containing medium size vesicles (500A) and a central core of mitochondria and neurofilaments; (2) a profile (SSV) containing small round vesicles (250-500 A) which is the most abundant and ubiquitous; (3) a profile (F) containing flattened or pleomorphic vesicles; (4) a profile (LSV) containing large oval egg shaped vesicles (750 A); and (5) a pale profile (PP) that contains oval and occasionally pleomorphic vesicles. MSV, SSV, and LSV terminals form asymmetrical contacts and F terminals form symmetrical contacts with both dendritic and vesicle-containing, pale profiles. The vesicle-containing, pale profile is both pre- and post-synaptic and participates in serial synapses. Following unilateral cortical ablations both dark and filamentous degeneration were observed in the ipsilateral basilar pontine gray.
在成年猕猴（恒河猴）和松鼠猴（松鼠猴）的脑桥基底灰质中，通过电子显微镜观察到了两种类型的神经元，即投射神经元和固有神经元，这两种神经元先前已在成年猕猴脑桥基底灰质的高尔基染色标本中被鉴定出来（库珀和福克斯，1976年）。投射神经元的细胞体直径可达37微米，其细胞质富含细胞器。高尔基体、核糖体和线粒体分布在细胞核周围，而粗面内质网虽然丰富，但通常局限于细胞体的一半。固有神经元的细胞体直径小于20微米，其细胞质显示出突出的核糖体，但其他细胞器较少。在脑桥基底的神经毡中已鉴定出五种突触形态；一种直径可达5微米，其余的直径为2微米或更小。它们是：（1）一种大的突触形态（MSV），含有中等大小的囊泡（500埃）以及线粒体和神经丝的中央核心；（2）一种突触形态（SSV），含有小的圆形囊泡（250 - 500埃），这是最丰富且分布最广泛的；（3）一种突触形态（F），含有扁平或多形性囊泡；（4）一种突触形态（LSV），含有大的椭圆形囊泡（750埃）；（5）一种浅色突触形态（PP），含有椭圆形且偶尔为多形性的囊泡。MSV、SSV和LSV终末形成不对称性接触，F终末与树突以及含囊泡的浅色突触形态都形成对称性接触。含囊泡的浅色突触形态既是突触前的也是突触后的，并参与串联突触。单侧皮质切除后，在同侧脑桥基底灰质中观察到了深色和丝状变性。
