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新生儿尿液中氨基酸排泄的初步筛查。

Preliminary screening of amino acids excretion in the urine of newly born babies.

作者信息

Iqbal J, Ilahi A, Qureshi M J, Gilani A H

出版信息

J Pak Med Assoc. 1977 Dec;27(12):440-2.

PMID:418194
Abstract

The paper attempts to characterize the qualitative as well as quantitative estimations of aminoacids in the urines of new born babies using two dimensional paper chromatography. The objective of this investigation was to know the extent of amino acid defects in these samples and to correlate such defects with the physical abnormalities in infants. Based on the overall results, it is inferred that phenylalanine excreted in the urine gave a positive response with PKU test and some particular amino acids are identified and estimated in the urine of new born babies to confirm the diagnosis of phenylketonuric patients.

摘要

本文尝试使用二维纸色谱法对新生儿尿液中的氨基酸进行定性和定量评估。本研究的目的是了解这些样本中氨基酸缺陷的程度,并将此类缺陷与婴儿的身体异常情况相关联。基于总体结果推断,尿液中排出的苯丙氨酸在苯丙酮尿症检测中呈阳性反应,并且在新生儿尿液中鉴定并评估了一些特定的氨基酸,以确诊苯丙酮尿症患者。

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