Swift M R, Finegold M J
Science. 1969 Jul 18;165(3890):294-5. doi: 10.1126/science.165.3890.294.
Skin fibroblasts in culture, derived from four unrelated patients with myotonic muscular dystrophy, contain abnormally large amounts of material with the staining characteristics of acid mucopolysaccharide. These cells also differ from normal cells in their pattern of growth at a high density in culture.
从四名患强直性肌营养不良的不相关患者身上获取的培养皮肤成纤维细胞,含有大量具有酸性粘多糖染色特征的异常物质。这些细胞在高密度培养时的生长模式也与正常细胞不同。