混合培养细胞致病性：一种检测小鼠白血病病毒在组织培养中生长情况的新试验。
Mixed culture cytopathogenicity: a new test for growth of murine leukemia viruses in tissue culture.
作者信息
Klement V, Rowe W P, Hartley J W, Pugh W E
出版信息
Proc Natl Acad Sci U S A. 1969 Jul;63(3):753-8. doi: 10.1073/pnas.63.3.753.
Abstract
Tissue culture cells of a Rous virus-induced rat tumor undergo syncytium formation when placed in contact with mouse embryo cell cultures infected with murine leukemia viruses. This phenomenon can be used as a cytopathic end point for isolating and titrating these viruses in tissue culture. The principle should be applicable to detection of leukemia viruses of other species.
摘要
劳斯病毒诱发的大鼠肿瘤的组织培养细胞，当与感染鼠白血病病毒的小鼠胚胎细胞培养物接触时，会发生合胞体形成。这种现象可作为在组织培养中分离和滴定这些病毒的细胞病变终点。该原理应适用于检测其他物种的白血病病毒。
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