Blume R S, Padgett G A, Wolff S M, Bennett J M
Can J Comp Med. 1969 Oct;33(4):271-4.
The percent of conventionally stained circulating neutrophils containing abnormal giant granules in Chediak-Higashi mink, cattle and mice is highly variable and strikingly less than the 100% found in neutrophils from similarly affected humans. In contrast, using either peroxidase or Sudan Black, it can be demonstrated that 100% of circulating neutrophils in all affected individuals of the four species studied contain the abnormal granules. Minor species differences in the shape of the granules were noted. The significance of these findings as well as the variations in granular staining by the several techniques employed are discussed.
在患有切-东综合征的水貂、牛和小鼠中，经传统染色的循环中性粒细胞中含有异常巨大颗粒的百分比变化很大，且显著低于在同样患病的人类中性粒细胞中发现的100%。相比之下，使用过氧化物酶或苏丹黑染色，可以证明在所研究的四个物种的所有患病个体中，100%的循环中性粒细胞都含有异常颗粒。注意到颗粒形状存在微小的物种差异。讨论了这些发现的意义以及所采用的几种技术在颗粒染色方面的差异。
