[抑霉唑（1-（2-（2,4-二氯苯基）-2-（2-丙烯氧基）乙基）-1H-咪唑）对扩展青霉中麦角甾醇生物合成的影响]
[Effect of imazalil (1-(2-(2,4-dichlorophenyl)-2-(2-propenyloxy) ethyl)-1H-imidazole) on biosynthesis of ergosterol in Penicillium expansum Link].
作者信息
Leroux P, Gredt M
出版信息
C R Acad Hebd Seances Acad Sci D. 1978 Feb 6;286(5):427-9.
PMID:418903
Abstract
Imazalil is a new fungicide effective against Penicillium molds on fruits after harvest. This compound inhibits ergosterol biosynthesis in mycelia of Penicillium expansum. The accumulation of 24--methylenedithydrolanosterol, obtusifoliol and 14 alpha-methyl-delta 8, 24(28)-ergostadienol in treated fungi suggests that imazalil blocks sterol C--14 demethylation.
摘要
抑霉唑是一种新型杀菌剂，对采后果实上的青霉菌具有防治效果。该化合物可抑制扩展青霉菌丝体中麦角甾醇的生物合成。在经处理的真菌中，24-亚甲基二氢羊毛甾醇、钝叶醇和14α-甲基-δ8,24(28)-麦角甾二烯醇的积累表明，抑霉唑可阻断甾醇C-14去甲基化作用。
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