Gordon H R, Phelps D, Blanchard K
Obstet Gynecol. 1979 Feb;53(2):151-6.
In an ongoing prospective study at 2 hospitals, 114 cesarean section patients were studied to determine whether giving ampicillin after umbilical cord clamping is as effective as perioperative ampicillin in reducing maternal postoperative morbidity. The same patients have also been studied to determine the effect of prophylactic cesarean section ampicillin on the newborn. Results have shown that prophylactic ampicillin initiated after cord clamping is as effective in reducing maternal morbidity as ampicillin initiated prior to the surgery. There is also no evidence from our study that the transplacental passage of prophylactic ampicillin increases immediate or delayed neonatal infections.
在两家医院正在进行的一项前瞻性研究中，对114例剖宫产患者进行了研究，以确定脐带结扎后给予氨苄西林在降低产妇术后发病率方面是否与围手术期使用氨苄西林同样有效。对同一批患者也进行了研究，以确定剖宫产预防性使用氨苄西林对新生儿的影响。结果表明，脐带结扎后开始预防性使用氨苄西林在降低产妇发病率方面与手术前开始使用氨苄西林同样有效。我们的研究也没有证据表明预防性使用的氨苄西林经胎盘传递会增加新生儿即时或延迟感染。
