Thompson R P, Williams R
Br Med J. 1970 Jan 17;1(5689):152-3. doi: 10.1136/bmj.1.5689.152.
The oral contraceptive chlormadinone acetate has been given for eight months to a woman who had developed jaundice during four pregnancies, and twice while taking a combined contraceptive pill. No side-effects or changes in liver function were observed. This is further evidence that progestogens used for contraception, and in particular those derived from hydroxyprogesterone, are less hepatotoxic than the oestrogenic components.
口服避孕药醋酸氯地孕酮已给予一名在四次妊娠期间均出现黄疸且在服用复方避孕药期间出现过两次黄疸的女性，用药八个月。未观察到副作用或肝功能变化。这进一步证明，用于避孕的孕激素，尤其是那些源自羟孕酮的孕激素，其肝毒性低于雌激素成分。
