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[去卵巢后大白鼠下颌下腺上皮变化的细胞化学与组织放射自显影分析]

[Cytochemical and histoautoradiographic analysis of changes in the epithelium of the submandibular gland of white rats following ovariectomy].

作者信息

Krichevskaia I E

出版信息

Probl Endokrinol (Mosk). 1979 Jan-Feb;25(1):71-5.

PMID:419095
Abstract

The author considers the dependence of the changes in the submaxillary gland epithelium in albino rats on the female sex hormone balance. Histochemical peculiarities of the secretory cells of the gland following ovariectomy were studied. The intensity of RNA and protein synthesis was studied by means of histautoradiography. The change of the nuclear and cytoplasmic area of the acinar cells, reduction of the RNA synthesis in all the gland parts after ovariectomy were demonstrated. The secretion synthesis intensity was disturbed; also the histochemical composition of the product secreted was altered. There occurs "masculinization" of the submaxillary gland epithelium in female rats, and secretion characteristic of males of these animals appears.

摘要

作者研究了白化大鼠颌下腺上皮变化与雌性激素平衡的关系。研究了卵巢切除术后该腺体分泌细胞的组织化学特性。通过组织放射自显影术研究了RNA和蛋白质合成的强度。结果表明,腺泡细胞的核和细胞质面积发生了变化,卵巢切除术后腺体所有部位的RNA合成均减少。分泌合成强度受到干扰,所分泌产物的组织化学组成也发生了改变。雌性大鼠颌下腺上皮出现“雄性化”,并出现了这些动物雄性的分泌特征。

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Probl Endokrinol (Mosk). 1979 Jan-Feb;25(1):71-5.
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