Dirnhofer R, Sigrist T
Acta Neuropathol. 1979 Feb 15;45(2):161-5. doi: 10.1007/BF00691896.
Based on the Kellie-Munro doctrine according to which the intracranial compartments--blood, brain, and CSF--are in a state of pressure and volume equilibrium, we examined if traumatic lesions of the liquor absorption passages could change the intracranial pressure (ICP). Therefore, we reviewed the arachnoid villi and granulations of patients which died as a result of head injuries. In cases of traumatic subarachnoidal hemorrhages the meshwork of arachnoid villi are filled throughout with blood. By microscopical examination we observed findings in the network of spaces of the villi like they are known in prestatic and static conditions of capillary system (clothing of erythrocytes). The pathophysiological significance of the findings, especially with regard to the dynamic of posttraumatic brain edema, is discussed.
根据凯利 - 芒罗学说,颅内腔室——血液、脑组织和脑脊液——处于压力和容积平衡状态,我们研究了脑脊液吸收通道的创伤性病变是否会改变颅内压(ICP)。因此,我们检查了因头部受伤死亡患者的蛛网膜绒毛和颗粒。在创伤性蛛网膜下腔出血的病例中,蛛网膜绒毛的网眼中充满了血液。通过显微镜检查,我们在绒毛间隙网络中观察到的现象与毛细血管系统在前列腺和静态条件下已知的现象相同(红细胞覆盖)。本文讨论了这些发现的病理生理意义,尤其是与创伤后脑水肿动态变化的关系。