人体中针对疟疾S抗原的抗体的免疫球蛋白特征

Wilson R J, McGregor I A

Immunology. 1973 Sep;25(3):385-98.

The electrophoretic mobility of antibodies to malarial S-antigens was usually γ. The same antigen-stimulated antibodies with different mobilities in different individuals. IgG antibodies and others probably belonging to the IgM class were detected. IgG dissociated from immune complexes contained light chains of λ type only in two cases and predominantly κ type in a third. This antibody cross-reacted with an antiserum to IgG2. Antibodies to other malarial antigens had restricted mobilities in the γ region.

针对疟疾S抗原的抗体的电泳迁移率通常为γ。相同的抗原在不同个体中刺激产生的抗体具有不同的迁移率。检测到了IgG抗体以及可能属于IgM类别的其他抗体。从免疫复合物中解离出的IgG仅在两例中含有λ型轻链，在第三例中主要为κ型轻链。这种抗体与抗IgG2抗血清发生交叉反应。针对其他疟疾抗原的抗体在γ区域具有受限的迁移率。