Wood W G, Harkins M M
Am J Clin Pathol. 1979 Jan;71(1):58-63. doi: 10.1093/ajcp/71.1.58.
Two elderly men who had fulminating systemic illnesses typical of angioimmunoblastic lymphadenopathy died in acute oliguric renal failure. In both, glomerular lesions were present. In one patient mild diffuse proliferative glomerulonephritis associated with necrotizing arteritis was seen, and in the other, minimal change was observed by light microscopy. In both, immunoglobulin-containing dense deposits within glomeruli were observed by fluorescence and electron microscopy, suggesting that the renal disease was mediated, at least partly, by deposition of immunoglobulin.
两名患有典型血管免疫母细胞性淋巴结病暴发性全身疾病的老年男性死于急性少尿性肾衰竭。两人均存在肾小球病变。其中一名患者可见轻度弥漫性增生性肾小球肾炎伴坏死性动脉炎，另一名患者经光学显微镜观察为微小病变。两人经荧光和电子显微镜检查均在肾小球内观察到含免疫球蛋白的致密沉积物，提示肾脏疾病至少部分是由免疫球蛋白沉积介导的。
