Orrison W W, Robertson W C
Arch Neurol. 1979 Jan;36(1):29-31. doi: 10.1001/archneur.1979.00500370059013.
In 1952, Cogan introduced the term "congenital ocular motor apraxia" (COA) to describe an abnormality of eye movements characterized by absent or defective voluntary horizontal gaze. Since his original description, there have been few subsequent reports of this disorder. A ten-year review of clinical records from the University of Wisconsin Hospitals disclosed eight patients with COA. In two patients subjected to neuroradiologic testing, agenesis of the corpus callosum was detected. Voluntary horizontal gaze appears to be a learned phenomenon, and defective interhemispheric transfer of visual information may be important in the pathogenesis of COA.
1952年，科根提出了“先天性眼球运动失用症”（COA）这一术语，用于描述以随意水平注视缺失或缺陷为特征的眼球运动异常。自他最初描述以来，关于这种疾病的后续报道很少。对威斯康星大学医院临床记录进行的十年回顾发现了8例COA患者。在2例接受神经放射学检查的患者中，检测到胼胝体发育不全。随意水平注视似乎是一种习得现象，视觉信息在半球间传递缺陷可能在COA的发病机制中起重要作用。
