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Arch Neurol. 1979 Feb;36(2):111-2. doi: 10.1001/archneur.1979.00500380081012.
Intractable sneezing is rare; the 12th case is reported here. Various causative factors have been identified in the literature; these include psychologic problems, cervical lymphadenitis, epilepsy, and allergy. The sneeze reflex consists of two phases, nasal and respiratory, which are mediated by cranial nerves V and VII and by brain-stem respiratory centers. Hypotheses that have been proposed to explain the multiple causation of sneezing are the concept of the trigeminal system as a central neuronal pool, optic-trigeminal summation, and parasympathetic generalization.
顽固性喷嚏较为罕见；本文报告第12例。文献中已确定了多种致病因素；这些因素包括心理问题、颈淋巴结炎、癫痫和过敏。喷嚏反射由两个阶段组成，即鼻腔阶段和呼吸阶段，分别由颅神经V和VII以及脑干呼吸中枢介导。为解释喷嚏多重病因提出的假说是将三叉神经系统视为一个中枢神经元池的概念、视-三叉总和以及副交感神经泛化。
