Brien T G, Fay J A, Griffin E A
Arch Dis Child. 1974 Mar;49(3):225-7. doi: 10.1136/adc.49.3.225.
The effective thyroxine ratio (ETR) was determined in 28 term and 17 premature infants at birth and in 17 infants aged 0 to 6 weeks. The mean values found were significantly higher than those in 20 adult euthyroid controls. Serum thyroxine (T), T resin uptake ratio (T RUR), free thyroxine index (FTI), and ETR were determined in 14 term infants at birth. It was concluded that the raised T was partly due to an increase in thyroxine binding globulin but that there was also a degree of true thyroid hyperactivity. Serum thyroxine alone was not considered a suitable index of thyroid function in infants and the free thyroxine index or the effective thyroxine ratio was preferred instead.
对28名足月儿、17名早产儿出生时以及17名0至6周龄婴儿测定了有效甲状腺素比率(ETR)。所发现的平均值显著高于20名甲状腺功能正常的成年对照者。对14名足月儿出生时测定了血清甲状腺素(T)、T树脂摄取比率(T RUR)、游离甲状腺素指数(FTI)和ETR。得出的结论是,T升高部分归因于甲状腺素结合球蛋白增加,但也存在一定程度的真正甲状腺功能亢进。单独的血清甲状腺素不被认为是婴儿甲状腺功能的合适指标,而游离甲状腺素指数或有效甲状腺素比率更受青睐。