普氏立克次体E株的研究。
Studies on the E strain of Rickettsia prowazeki.
作者信息
Kazár J, Brezina R, Urvölgyi J
出版信息
Bull World Health Organ. 1973;49(3):257-65.
Abstract
Cultivation of E strain of Rickettsia prowazeki in mouse lung resulted in a marked increase in virulence for guinea pigs following 12 passages (but not 6 passages) in both immunosuppressed and normal mice. Attempts at passaging E strain in normal guinea pigs were unsuccessful. Isolates of E strain in the chicken embryo yolk sac either from testes and peritoneal washings or from the brain of immunosuppressed guinea pigs did not show enhanced virulence for guinea pigs.
摘要
普氏立克次体E菌株在小鼠肺中培养，在免疫抑制和正常小鼠中传代12次（而非6次）后，对豚鼠的毒力显著增加。在正常豚鼠中传代E菌株的尝试未成功。从睾丸和腹腔冲洗液或免疫抑制豚鼠的脑中获取的鸡胚卵黄囊中E菌株分离物，对豚鼠并未表现出增强的毒力。
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Bull World Health Organ. 1973;49(3):257-65.
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Am J Hyg. 1949 May;49(3):313-20. doi: 10.1093/oxfordjournals.aje.a119281.
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[On the susceptibility of Macacus rhesus monkeys to vaccinal strain E of Rickettsia prowazekii].[恒河猴对普氏立克次体疫苗株E的易感性]
Vopr Virusol. 1962 Mar-Apr;7:225-8.
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