感染猫细小核糖核酸病毒的猫的急性期和恢复期抗体差异。
Differences in acute and convalescent-phase antibodies of cats infected with feline picornaviruses.
作者信息
Olsen R G, Kahn D E, Hoover E A, Saxe N J, Yohn D S
出版信息
Infect Immun. 1974 Aug;10(2):375-80. doi: 10.1128/iai.10.2.375-380.1974.
Complement fixation inhibiting and complement-fixing antibodies were demonstrated in sera from cats during the acute and convalescent stages, respectively, of feline picornavirus infections. Complement-fixing antibody activity was present in 19S and 7S globulins, whereas complement fixation inhibiting antibody activity was confined to the 7S globulins. Sera with complement-fixing antibody and sera with complement fixation inhibiting antibody were also shown to have neutralizing and precipitating antibodies. In a study of antibody responses to homotypic and heterotypic strains of feline picornavirus, less serological cross-reactions were observed between strains of feline picornavirus in sera from cats in the acute phase of feline picornavirus infection than in the convalescent phase. The temporal relationship of complement fixation inhibiting and complement-fixing antibody responses of cats after acute viral respiratory infections is contrasted with previously observed antibody response in cats to feline leukemia virus.
在猫细小核糖核酸病毒感染的急性期和恢复期血清中，分别证实了补体结合抑制抗体和补体结合抗体。补体结合抗体活性存在于19S和7S球蛋白中，而补体结合抑制抗体活性则局限于7S球蛋白。具有补体结合抗体的血清和具有补体结合抑制抗体的血清也显示出具有中和抗体和沉淀抗体。在一项关于猫细小核糖核酸病毒同型和异型毒株抗体反应的研究中，与恢复期相比，在猫细小核糖核酸病毒感染急性期猫血清中，该病毒不同毒株之间的血清学交叉反应较少。猫急性病毒性呼吸道感染后补体结合抑制抗体和补体结合抗体反应的时间关系，与先前观察到的猫对猫白血病病毒的抗体反应形成对比。
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