Naoum P C
Rev Bras Pesqui Med Biol. 1979 Jun;12(2-3):213-21.
The importance of the haemoglobinopathies, mainly thalassaemia, as a public health problem has been emphasized. The establishment of methods for detection and diagnosis of haemoglobinopathies is the major step in laboratories dedicated to screening anemias. Tables for the diagnosis of alpha and beta thalassaemia are proposed, the methods to identify abnormal haemoglobins are discussed and a map with the relative mobilities of 115 abnormal haemoglobins by electrophoresis in alkaline buffer is shown.
血红蛋白病,主要是地中海贫血,作为一个公共卫生问题的重要性已得到强调。建立血红蛋白病的检测和诊断方法是致力于贫血筛查的实验室的主要步骤。本文提出了α和β地中海贫血的诊断表,讨论了鉴定异常血红蛋白的方法,并展示了一张在碱性缓冲液中通过电泳得出的115种异常血红蛋白相对迁移率的图谱。