Darsee J R, Mikolich J R, Nicoloff N B, Lesser L E
Circulation. 1979 Apr;59(4):619-22. doi: 10.1161/01.cir.59.4.619.
We determined the prevalence of mitral valve prolapse (MVP) in presumably healthy young men by studying 107 male house officers and medical students with cardiac auscultation in the supine, sitting and standing positions. Echocardiograms were performed at rest in the supine position before and after amyl nitrite inhalation and were obtainable in 101 subjects. Eleven of the 101 subjects had abnormal findings on auscultation: four had an isolated click and seven had a click and late systolic murmur. Correlation of the independent auscultatory and echocardiographic data in the 101 subjects showed that all seven of the subjects with a click and a murmur had echocardiographic evidence of prolapse. None of the 90 subjects with normal auscultation or the four with an isolated click had an abnormal echocardiogram. All seven subjects with MVP had thoracic skeletal abnormalities, but only one was symptomatic. These data suggest that the prevalence of MVP in healthy young males is similar to the reported 6-10% prevalence in healthy young females.
我们通过对107名男性住院医师和医学生在仰卧位、坐位和站立位进行心脏听诊，来确定健康年轻男性中二尖瓣脱垂（MVP）的患病率。在亚硝酸异戊酯吸入前后，于仰卧位静息状态下进行超声心动图检查，101名受试者可获得检查结果。101名受试者中有11人听诊发现异常：4人仅有喀喇音，7人有喀喇音和收缩晚期杂音。对101名受试者独立的听诊和超声心动图数据进行相关性分析显示，所有7名有喀喇音和杂音的受试者均有超声心动图证实的脱垂。90名听诊正常的受试者或4名仅有喀喇音的受试者中，无人超声心动图异常。所有7名MVP受试者均有胸廓骨骼异常，但只有1人有症状。这些数据表明，健康年轻男性中MVP的患病率与报道的健康年轻女性6%-10%的患病率相似。
