Biro L, Price E
Cutis. 1979 Mar;23(3):348-50.
A squamous cell carcinoma developed on the chin of a seventy-five year old woman of Irish extraction. This tumor had recurred following standard means of therapy and resisted treatment by chemosurgery. The patient had used a cream containing 5-fluorouracil for several years prior to the appearance of this tumor. The increased incidence of skin cancer and its possible cause is briefly discussed and the role of immunobiologic factors in the development of squamous cell carcinomas is mentioned.
一名七十五岁、有爱尔兰血统的女性下巴上长出了鳞状细胞癌。该肿瘤在接受标准治疗手段后复发,且对化学外科治疗有抵抗性。在这个肿瘤出现之前,患者已经使用含5-氟尿嘧啶的乳膏数年。文中简要讨论了皮肤癌发病率增加及其可能的原因,并提及了免疫生物学因素在鳞状细胞癌发生过程中的作用。