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[成人癫痫。我们能区分出进行性类型吗?]

[Epilepsies in the adult. Can we distinguish progressive types?].

作者信息

Martin F

出版信息

Schweiz Arch Neurol Neurochir Psychiatr. 1974;115(2):209-27.

PMID:4219861
Abstract

Electro-clinical, neuro-radiologic and socio-professional study of 100 epileptic adults, followed by the same physician during 12 to 20 years (average 15 1/2 years), now 30 to 75 years old, all cases of evolutive pathology being excluded. The evolution statistically is more favourable when the epilepsy: has developed late (between 21 and 30 years); ils described as "idiopathic", or with small primary lesion; is characterized by primary generalized fits with strong convulsive component, occurring preferably at awaking. The evolution is less favourable, even unfavourable, when the epilepsy: is secondary to a severe encephalopathy or to extensive focal lesions; has developed during childhood; is characterized by fits with partial start, little tendency to secondary convulsive generalization, and occurring any time of the day or bound to sleep.

摘要

对100名成年癫痫患者进行电临床、神经放射学和社会职业研究,由同一位医生随访12至20年(平均15.5年),患者目前年龄在30至75岁之间,所有进行性病变病例均被排除。从统计学角度来看,当癫痫具备以下情况时病情进展更有利:发病较晚(21至30岁之间);被描述为“特发性”或原发性病变较小;以原发性全身性发作且惊厥成分强烈为特征,最好在醒来时发作。而当癫痫具备以下情况时病情进展较不利,甚至不利:继发于严重脑病或广泛的局灶性病变;在儿童期发病;以部分起始发作、继发性惊厥泛化倾向小且在一天中任何时间发作或与睡眠相关为特征。

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