Friedlander C, Nerubay J, Katznelson A, Nebel L
Isr J Med Sci. 1979 Jan;15(1):38-42.
Autogenous transplantation of periosteum was performed in 60 rats. Periosteum was transferred from the femur to the spinal column in the region of thoracic vertebra 8 to lumbar vertebra 2. Follow-up included histological examination and microradiography. New bone formation occurred late and the bones were of a heterotopic nature; a solid arthrodesis was not achieved. Free periosteal grafts do not exhibit the relatively predictable behavior of periosteal flaps. Greater understanding at the biomolecular level may be required before free periosteal grafts can be introduced into routine clinical practice.
对60只大鼠进行了自体骨膜移植。将骨膜从股骨转移至第8胸椎至第2腰椎区域的脊柱。随访包括组织学检查和微放射照相。新骨形成出现较晚，且所形成的骨具有异位性质；未实现牢固的关节融合。游离骨膜移植并不表现出骨膜瓣相对可预测的行为。在将游离骨膜移植引入常规临床实践之前，可能需要在生物分子水平上有更深入的了解。
