Marsch W C, Stüttgen G, Wegener H H
Hautarzt. 1979 Jan;30(1):12-5.
Report of a 28-year-old female patient with a metastasizing soft tissue sarcoma confined to the oral mucosa and subcutis. The basic disease attracted clinical attention as a nodular febrile nonsuppurative panniculitis (Pfeifer-Weber-Christian disease). Perivascular tumor cells in the subcutis obviously induced localized fat necroses. Ultrastructurally, the pathological cells showed no indicative cytological characteristics other than a close association with reticulin fibers. Apparently, a metastasizing tumor disease can be concealed under the clinical picture of a nodular febrile non suppurative panniculitis--as a paraneoplastic syndrome.
一名28岁女性患者的报告，其转移性软组织肉瘤局限于口腔黏膜和皮下组织。该基础疾病作为结节性发热性非化脓性脂膜炎（费弗-韦伯-克里斯蒂安病）引起了临床关注。皮下组织中的血管周围肿瘤细胞明显诱导了局部脂肪坏死。超微结构上，除了与网状纤维紧密相关外，病理细胞没有显示出指示性的细胞学特征。显然，转移性肿瘤疾病可能隐藏在结节性发热性非化脓性脂膜炎的临床表现之下——作为一种副肿瘤综合征。
