Bönniger F, Burg G
Hautarzt. 1979 Feb;30(2):92-4.
Report of a 59 year old man who suffered from spontaneously healing multiple keratoakanthomas of the face and neck for five years. Multiple keratoakanthomas, multiple primary squamous-cell carcinomas with spontaneous healing and tumor-like keratoses probably are variants of the same disease. The etiology of multiple keratoakanthomas is unknown. Clinically as well as histologically they are similar to solitary keratoakanthomas and show spontaneous healing. Thorough clinical control of the patients is necessary because of the possible transformation into squamous cell carcinomas.
一名59岁男性患者的报告，其面部和颈部多发性角化棘皮瘤自发愈合达五年之久。多发性角化棘皮瘤、具有自发愈合的多发性原发性鳞状细胞癌以及肿瘤样角化病可能是同一种疾病的不同变体。多发性角化棘皮瘤的病因尚不清楚。在临床和组织学上，它们与孤立性角化棘皮瘤相似，并表现出自发愈合。由于可能转变为鳞状细胞癌，因此对患者进行全面的临床监测是必要的。
