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新生雄性和雌性大鼠弓状核的细胞学研究

Cytology of the arcuate nucleus in newborn male and female rats.

作者信息

Walsh R J, Brawer J R

出版信息

J Anat. 1979 Jan;128(Pt 1):121-33.

PMID:422472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1232966/
Abstract

Five coronal levels of the arcuate nuclei in newborn male and female rats were examined with the transmission electron microscope. The nuclei from male and female neonates appear similar in all respects. All levels exhibit a significant population of round to oval cell profiles with large centrally located nuclei and scant cytoplasm which contains predominantly ribosomes, sparse mitochondria, and a few short cisternae of rough endoplasmic reticulum. These organelle-poor cell profiles resemble neuroblasts in other parts of the developing CNS. The arcuate nuclei of neonates also exhibit some cell profiles with the variety and quantity of organelles characteristic of mature neurons in the arcuate nuclei of adult rats. In addition, the neonatal arcuate nuclei show a paucity of synapses with apparent immaturity of those present, and numerous structures identified as growth cones. Definitive macroglia are not present in the arcuate nuclei of newborn rats.

摘要

用透射电子显微镜检查了新生雄性和雌性大鼠弓状核的五个冠状层面。雄性和雌性新生大鼠的细胞核在各方面看起来都相似。所有层面均显示出大量圆形至椭圆形的细胞轮廓，细胞核位于中央且较大，细胞质稀少，主要含有核糖体、稀疏的线粒体和一些短的粗面内质网池。这些细胞器较少的细胞轮廓类似于发育中的中枢神经系统其他部位的神经母细胞。新生大鼠的弓状核还显示出一些细胞轮廓，其细胞器的种类和数量具有成年大鼠弓状核中成熟神经元的特征。此外，新生弓状核的突触较少，且现有的突触明显不成熟，还有许多被鉴定为生长锥的结构。新生大鼠的弓状核中不存在明确的大胶质细胞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/ae3920393ea9/janat00241-0129-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/0b6befd77270/janat00241-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/f8e254f1960b/janat00241-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/90dc3c8d1a2c/janat00241-0124-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/1e747d0950e0/janat00241-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/dc6cdc86738a/janat00241-0126-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/959f600dbb5b/janat00241-0126-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/8c94e1a58b68/janat00241-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/80f629c3ef34/janat00241-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/925120016827/janat00241-0129-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/ae3920393ea9/janat00241-0129-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/0b6befd77270/janat00241-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/f8e254f1960b/janat00241-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/90dc3c8d1a2c/janat00241-0124-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/1e747d0950e0/janat00241-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/dc6cdc86738a/janat00241-0126-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/959f600dbb5b/janat00241-0126-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/8c94e1a58b68/janat00241-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/80f629c3ef34/janat00241-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/925120016827/janat00241-0129-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eac7/1232966/ae3920393ea9/janat00241-0129-c.jpg

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